A twister flattened entire blocks of homes in a small Illinois town during the night as violent storms ravaged the Midwest and South, killing at least 12 people.
Winds also ripped through the country music mecca of Branson, Missouri, damaging some of the city's famous theaters.
The tornado that blasted Harrisburg in southern Illinois, killing six, was an EF4, the second-highest rating given to twisters based on damage. Scientists said it was 180m wide with winds up to 270 km/h.
Townspeople in the community of 9000 were sorting through piles of debris and remembering their dead while the winds still howled.
Not long after the storm, Darrell Osman raced to his mother's home, arriving just in time to speak to her before she was taken to a hospital with a head injury, a severe cut to her neck and a broken arm and leg. Mary Osman died a short time later.