Following the April attack, US President Donald Trump ordered an air strike against the Assad-controlled air field where the attack was believed to have been carried out.
At the time, Trump said that Assad's use of chemical weapons against innocent women and children made action inevitable.
"When you kill innocent children, innocent babies, babies, little babies, with a chemical gas that is so lethal - people were shocked to hear what gas it was," Trump said after the attack. "That crosses many, many lines, beyond a red line, many, many lines."
The US military maintains a variety of weapons in the region that could be used in the event of another strike, including manned and unmanned aircraft in several Middle Eastern countries. But the most likely scenario is probably a strike using naval assets, which can be launched with fewer diplomatic issues than using bases in allied countries like Turkey or the United Arab Emirates.
The Navy launched Tomahawk missiles at a Syrian military airfield on April 6 in response to a previous alleged chemical weapons attack, using two guided-missile destroyers in the eastern Mediterranean Sea, the USS Ross and USS Porter, to do so.
Presently, the Pentagon has several ships nearby, including the George H.W. Bush Strike Group. Anchored by the aircraft carrier by the same name, it includes dozens of fighter jets and several smaller vessels, including the guided-missile destroyers USS Laboon and USS Truxtun and the guided-missile cruisers USS Philippine Sea and USS Hue City.
A point of contention for the Pentagon after the last strike was the Syrian regime's alleged use of a nerve agent, like sarin. It is far deadlier than some other chemical weapons that US military and intelligence officials say that the regime has used, such as chlorine.