The US military said it carried out airstrikes in eastern Syria that targeted areas used by militias backed by Iran's paramilitary Revolutionary Guard.
There was no immediate acknowledgment by Syria's state-run media of the strikes hitting Deir Ez-Zor. Iran as well did not acknowledge the attack.
The US military's Central Command said the strikes "took proportionate, deliberate action intended to limit the risk of escalation and minimise the risk of casualties". It did not identify the targets, or offer any casualty figures from the strikes, which the military said came at the orders of President Joe Biden.
"Today's strikes were necessary to protect and defend US personnel," Central Command spokesman Joe Buccino said in a statement.
The colonel added the attack was in response to an attack targeting US forces. That attack saw drones allegedly launched by Iranian-backed militias target the al-Tanf Garrison used by American forces. US Central Command described the assault as causing "zero casualties and no damage" at the time.
