So, like any loving president would do for their vice president pal, he reached across his wife to place a tender hand on Pence's thigh.
However, the Vice President didn't seem to appreciate the loving gesture and appeared to be visibly uncomfortable, with his lips pressed tightly together and hands gripping the bottom of his suit jacket.
The photo has been shared around social media, with people claiming they just can't stop looking at the awkward scene.
"I was able to complete a conference call while staring at this photo the whole time," one Twitter user wrote.
"Dude! Your wife is right there!" another said.
In stark contrast to Pence's visible discomfort, people have pointed out that Melania looked pretty content with the whole situation.
One user asked: "Why is Melania smiling so much when Trump has his hand on Pence's leg. That is just making her glow!"
"Melania seems relieved it's not hers," another person wrote.
Other social media users suggested that Trump never intended to touch Pence at all, but just overshot when reaching for Melania's leg.
"He was reaching for Melania and she moved out of the way, so Pence got the grab. Trump can't tell the difference and Pence is just waiting to move into the driver's seat, so he has to pretend he doesn't notice," someone explained.
Was it a simple mistake or an awkward moment born from a comforting gesture? We may never know.
