Tabloid reporting of Ms Nicholson's win at the National Scrabble championships in 2010 mocked her as a man in dress, and one columnist insinuated - under the headline "Why we're all Scrabbling to put on a frock" - that it was unseemly how many people were "cross-dressing".
Ms Nicholson was treated at a psychiatric clinic last year and later supported at home by community psychiatric nurse Clive Guyo. He told the inquest she had previously considered suicide after visiting Manchester as she was scared of returning to Carlisle.
"She described Carlisle as hostile to people who are different," Mr Guyo said. "She spoke of facing verbal abuse while walking in the streets because of how she appeared to other people. Schoolchildren were often the worst for making fun of her and verbally abusing her."
Mr Guyo said she clung to the belief that her life would be better if only she could leave Carlisle. "She had a negative view of Carlisle based on past experience," he said. "She felt stigmatised."
The inquest heard that Ms Nicholson wanted to move to Newcastle but was told she would be classed as "intentionally homeless" if she left her flat, making it hard to find other social housing. She had no money to rent privately.
In the five weeks before her death, she was not contactable, though Mr Guyo tried to visit and help her.
Rebecca Mellor, a close friend of Ms Nicholson's, said: "Mikki was fiercely intelligent, exploring her gender identity, and had a vivacious character. She frequently felt at odds with the world because of her intelligence [and] gender identity."
Coroner David Roberts concluded yesterday that Ms Nicholson had deliberately killed herself but that she had been well supported by psychiatric services. Cumbria Partnership Trust, which provided psychiatric care, is now discussing providing specialist support for transgender people in north Cumbria.
Where to get help:
• Lifeline: 0800 543 354 (available 24/7)
• Suicide Crisis Helpline: 0508 828 865 (0508 TAUTOKO) (available 24/7)
• Youth services: (06) 3555 906
• Youthline: 0800 376 633
• Kidsline: 0800 543 754 (4pm to 6pm weekdays)
• Whatsup: 0800 942 8787 (1pm to 11pm)
• The Word
• Depression helpline: 0800 111 757 (available 24/7)
• Rainbow Youth: (09) 376 4155
• CASPER Suicide Prevention
If it is an emergency and you feel like you or someone else is at risk, call 111.
- The Independent