George Osborne yesterday fired the opening shots of the campaign against Scottish independence, warning that Scotland would risk a euro-style debt crisis if it left the United Kingdom.
The British Chancellor also claimed that Scotland standing alone would be unable to withstand a second financial shock and would deter foreign investors.
He spoke out as Downing St signalled its belief that Scotland would have to accept its share of the toxic assets of the Royal Bank of Scotland following its £46 billion ($89 billion) bailout by the British taxpayer.
The Coalition Government believes the SNP Administration headed by Alex Salmond would be vulnerable to a challenge over the practicalities of how an independent Scotland would operate - a stance shared by Labour leaders.
Pro-Union politicians are now preparing to focus the debate on four questions - what currency would operate north of the border, what proportion of Britain's debts Scotland would have to assume, the future of the armed forces and whether border controls would have to be introduced.