The National Park Service, which oversees the Mall, has fielded 33 per cent more requests this year for permits to protest on Washington's federal land than it had at this time last year, said Mike Litterst, a spokesman for the agency.
The Park Service had received 197 permit requests for demonstrations as of Wednesday, compared with 148 at the same time in 2016.
That number does not include unpermitted protests and others that have spontaneously unfolded in front of buildings, such as the US Capitol and Environmental Protection Agency headquarters.
The Earth Day Network, the organisation that spearheads the annual Earth Day rally and affiliated events worldwide, began planning tomorrow's rally long before Election Day. This year, scientists who say the Trump Administration has disregarded or devalued scientific research are joining the effort - a rare position for the typically apolitical field of science.
The rally at the Washington Monument will feature dozens of short speeches and videos, said Kathleen Rogers, president of the Earth Day Network. Attendees will march toward the US Capitol.
The theme of this year's event is environmental and climate literacy. Celebrity scientist Bill Nye is among the speakers.
"Hell hath no fury like a scientist scorned, and that's essentially where we are," Rogers said.
"People will be marching because their integrity and honesty has been called into question. This is a new and energised constituency - they just happen to be wearing lab coats."
Protesters at recent marches say they have channelled their discontent with the new Administration's policies into the demonstrations.
At the Tax March last weekend, attendees said the protests were effective, crediting demonstrations throughout the country with thwarting Trump's travel ban plans and stymieing the Republicans' proposed healthcare plan.
"I feel this keeps me sane," said Susie Sinclair-Smith, a Maryland resident who attended the Women's March and Tax March and plans to attend the rally this weekend. "I'm hoping I get more energised by coming here."