A video set to precede her speech shows Harris from her days on the presidential trail saying she will fight for women — especially those of colour, according to a snippet released early by the campaign. Harris will say in her address that she is committed to the values her mother taught her: "To walk by faith, and not by sight, and to a vision passed on through generations of Americans — one that Joe Biden shares."
"A vision of our nation as a beloved community — where all are welcome, no matter what we look like, where we come from or who we love," Harris plans to say, according to early excerpts. "A country where we may not agree on every detail, but we are united by the fundamental belief that every human being is of infinite worth, deserving of compassion, dignity and respect."
She will also hit Trump: "Right now, we have a President who turns our tragedies into political weapons. Joe will be a president who turns our challenges into purpose."
The senator's advisers say Harris will tell her story while highlighting the examples and experiences of others.
"I hope that they see themselves in her when they hear her speak," Mari Urbina, national director of Indivisible, a progressive advocacy group, said of young first- and second-generation immigrants across the country. "And that they are motivated to understand that, not only do they have to be part of getting us out of this nightmare, but that they also can feel part of this historic change that we're all about to embark on."
In a virtual address Wednesday to the convention's Asian American and Pacific Islander Caucus, Harris said she would deliver her speech "knowing that I stand on the shoulders of so many people who are on this call and those who came before us."
The daughter of Jamaican and Indian immigrants, Harris has shone in key moments before.
She was lauded for drawing a crowd of 20,000 to the announcement of the start of her presidential campaign in Oakland last year. Her subsequent tough questioning of two Trump nominees, Brett Kavanaugh for Supreme Court justice and Bill Barr for attorney general, during Senate confirmation proceedings was a similar high point, as was her broadsiding Biden during a debate over his opposition to busing in the 1970s to integrate public schools.
But Harris also launched her presidential bid with expectations that she would electrify the field, only to see her campaign struggle to find a consistent message and fizzle — with the California senator dropping out months before the first votes were cast.
Convention addresses are often the most important for those selected as vice-presidential candidates but are also only the start of a far bigger role in public political consciousness, should their ticket win. There's potentially even deeper repercussions for Harris, though, since she could be called upon to step into the role of party standard-bearer as soon as 2024, should Biden — who will be 81 by then — opt not to seek a second term.
Biden hasn't expressly said he'd serve just a single term, but he has talked openly about being a bridge to a new generation — setting up Harris as a natural successor.
Adrianne Shropshire, executive director of BlackPAC, which works to mobilise African American voters nationally, said Harris will necessarily stay focused on defeating Trump in November, not future presidential races. But she said her speech will likely carry special significance for women around the country that could resonate for years.
"The historic nature of this, I don't think can be overstated," Shropshire said. "It will be a really profound moment for women."
The campaign is also deeply personal for Harris. During her first appearance with Biden last week, she spoke of her friendship with the former vice-president's son Beau, who died of brain cancer in 2015. He and Harris became close while both were state attorneys general.
"He really was the best of us. And I would ask him, 'Where'd you get that, where'd this come from?' He'd always talk about his dad," said Harris, her voice thick with emotion, during her first joint appearance with Biden last week at a high school gymnasium near his home in Delaware.
The former vice-president said that relationship had made Harris "an honorary Biden for quite some time".
-AP