Quickly, the "word" covfefe began trending.
"Don't talk to me until I've had my #covfefe," wrote one user.
"What's even the point of CNN if they're not going commercial-free with #covfefe coverage?" inquired another.
"The next time I go to Starbucks I'm gonna order a grande #covfefe," wrote one thirsty user.
The word "covfefe" does not appear in the Merriam-Webster Dictionary. When searching for it on the company's website, the dictionary suggests "coffee," "coven," "cover," "covet," "covey" and "cuvee."
Twitter users certainly came up with a few definitions for the word, such as coffee or a synonym to "The Lion King's" "hakuna matata." (It means no worries, for the rest of your days.)
Others suggested it might make a great band, or perhaps human, name.
Fusion even launched a poll asking others to weigh in on the strange word's pronunciation.
Some, meanwhile, defended Trump, pointing out that accidentally sending a half-typed tweet is a human error.
The President deleted the tweet early morning DC time, while retweeted a tweet by one of his favourite shows - Fox and Friends.
The plot thickened when he addressed the tweet.