John Key is shocked about the Pope's resignation, describing the move by the 85-year-old as a "brave call".
Pope Benedict XVI has declared he lacked strength of mind and body to continue as head of the Catholic Church worldwide, and will step down on February 28 - becoming the first pontiff to do so in 600 years.
"This is a position where people normally carry on for all of their natural life once they've been appointed to being the pope, so it's a very surprising move," said John Key told TV3's Firstline.
"He obviously feels the great burden and responsibility of leading the Catholic Church and maybe just feels his health isn't allowing him to discharge his responsibilities adequately and at the level he would want," he said.
The Pope made the announcement during a meeting of Vatican cardinals.