A Pakistan International Airlines (PIA) aircraft has crashed in a residential area near the Karachi Airport.
Pakistan's Aviation Ministry said the flight was carrying 99 passengers and 8 crew members.
Mayor of Karachi at scene of crash said none of the 107 passengers, crew survived.
Flight PK8303 took off from Lahore and was due to land at 2.30pm local time in Karachi but went missing from the radar, Pakistan Airlines spokesman Abdullah Khan told CNN.