In addition to sexism, Obama singled out the deep partisan divide as another reason for what he said is likely to be a close election. "Structurally we already have these divisions," Obama said. "It is going to be hard to overcome those."
Obama contrasted Trump with the two previous Republican nominees - both of whom he described as qualified to serve as president. "I couldn't say that electing Mitt Romney would be an unmitigated disaster," he said.
Obama described Trump as someone who "shows no interest in even gaining the rudimentary knowledge required to make really hard decisions" and whose campaign has sought to exploit the country's worst and most divisive impulses.
"It is an infomercial. It's a reality show," Obama said of the Trump campaign.
The President also pointed to recent statistics from the US Census Bureau that showed that middle-class and poor Americans had their best year of income gains in decades as proof that his economic polices are working.
"We now have one candidate in this race who is prepared to carry on that kind of governance," Obama said, referring to Clinton.