Thirty-five people were killed and 150 injured when multiple explosions tore through the central mosque in Kano, police said.
The survivors had various degrees of injury in the Friday blasts in Nigeria's second-largest city, State Deputy Police Commissioner Sanusi Lemu said.
Hundreds had gathered to listen to a sermon in a region terrorised by attacks from the militant group Boko Haram.
Witnesses said heavy smoke could be seen billowing in the sky from far away. Immediately after the blasts, hundreds of angry youths took to the streets in riots, throwing stones, brandishing sticks and shouting at security officials.
Boko Haram has not claimed responsibility, but the attack bears the hallmarks of the militant group that has made numerous such attacks in northern Nigeria, including in Kano. In September, two suicide bombers killed at least 15 students at a government college and in July, five suicide bombings occurred in a week. More than 1500 have been killed this year in the insurgency.