Scientists have found evidence of a resistant form of malaria in Uganda, a worrying sign that the top drug used against the parasitic disease could ultimately be rendered useless without more action to stop its spread.
Researchers in Uganda analysed blood samples from patients treated with artemesinin, the primary medicine used for malaria in Africa in combination with other drugs. They found that by 2019, nearly 20 per cent of the samples had genetic mutations suggesting the treatment was ineffective. Lab tests showed it took much longer for those patients to get rid of the parasites that cause malaria.
Drug-resistant forms of malaria were previously detected in Asia, and health officials have been nervously watching for any signs in Africa, which accounts for more than 90 per cent of the world's malaria cases. Some isolated drug-resistant strains of malaria have previously been seen in Rwanda.
"Our findings suggest a potential risk of cross-border spread across Africa," the researchers wrote in the New England Journal of Medicine, which published the study on Wednesday.
The drug-resistant strains emerged in Uganda rather than being imported from elsewhere, they reported. They examined 240 blood samples over three years.