Madeleine McCann's parents have admitted to being left "haunted" at a question their 3-year-old daughter asked the morning of her disappearance.
Maddie disappeared from the family's apartment on the evening of May 3, 2007, while on holiday in Portugal.
But in Kate McCann's book, Madeleine McCann: Our Daughter's Disappearance and the Continuing Search for Her, the 51-year-old mother detailed their concern for Maddie just hours before she disappeared.
In her book, which was released in 2011, Kate says a question Maddie asked her left her "puzzled" and now "haunted".
"At breakfast time, Madeleine had a question for us: 'Why didn't you come when Sean and I cried last night?'," she wrote.
"It was not impossible, but it seemed implausible.
"Not for a moment did we think there might be some sinister reason for this occurrence, if indeed anything had occurred.
"If only foresight came as early to us as hindsight.
"Within hours, the explanation for this would seem hugely important, and so haunted have I been ever since by Madeleine's words that morning that I've continued to blame myself for not sitting down and making completely certain there was no more information I could draw out of her.
"This could have been my one chance to prevent what was about to happen, and I blew it.
"There was absolutely nothing to give me any reason for suspicion and we can all be clever after the event.
"But it is my belief there was somebody either in or trying to get into the children's bedroom that night, and that is what disturbed them."
In her book, Kate also explains the system of "child-checking" that the McCanns and their group of friends had decided on, as they dined in the resort's tapas restaurant close by.
She says: "We now bitterly regret it and will do so until the end of our days."
The recent spotlight on Maddie's disappearance comes following the Netflix series The Disappearance of Madeleine McCann.
The eight-part documentary was not supported by the McCann family.