The 40-year old centrist was under intense pressure to avoid fresh damage and bloodshed after successive weekends of violent riots in Paris and other cities that have seen 4523 arrests and already stripped France of 0.1 per cent of GDP growth, according to its finance minister.
Thousands of "gilets jaunes" have been blocking roads and roundabouts for almost a month in an outpouring of anger over perceived high taxes for the poor and overwhelming accusations that he is an arrogant, out-of-touch "president of the rich".
Many were furious that he had remained silent to their fury, hunkered down in the Elysée over the past few days despite the ambiance of quasi-insurrection. Many simply want the ex-banker to step down.
But Macron stood firm on his controversial decision to partially scrap France's totemic wealth tax - another key demand from many "gilets jaunes". To do so, he said, would "weaken us".
The President, who has abruptly become the least popular leader in modern French history after a dream start, said that the anger of peaceful "yellow vest" protesters was "fair and can be our opportunity".
He said that their movement was the result of "40 years of malaise" that "we ended up getting used to.. out of cowardice".
However, he slammed the "unacceptable outpouring of violence" of vandals. "No anger justifies attacking a police officer or public property."
Macron also made it clear he intended to push on with planned reforms of social security and pensions. He also said he would start a tour of France's mayorships during three months of local talks. "We will not simply start our lives back up as before as if nothing had changed."
Despite a string of concessions ahead of his speech, including scrapping the green tax on diesel and petrol that sparked the unrest, many protesters had already taken to social media to call for an "Act V" of radical action.
"I have never known under the Fifth Republic such hostility against a president," said political analyst Jérôme Jaffré. "It is a personal affair between a part of the country and president, hence the incredible stakes of this speech. This is the start of Act II of his presidency where Macron II fiercely has criticised Macron."
In one hall in Galargues, southern France, some pensioners applauded at the tax breaks but many said they would continue the protests. Karl Toquard, yellow vest spokesman at a roundabout in Gaillon, Normandy, said: "There was nothing for us. We're staying put."