A landslide in Colombia's south-western border province of Putumayo sent mud and debris crashing onto houses, killing 127 people and injuring at least 400.
Heavy rains caused several rivers to overflow, pushing sediment and rocks onto buildings and roads in the provincial capital of Mocoa and immobilising cars in several feet of mud.
The Red Cross reports that 127 people are dead, 220 missing and 400 injured.
President Juan Manuel Santos arrived in Mocoa to assess the damaage and and declared a state of emergency.
"We have sent a team of 150 people to make our response effective and machinery began work immediately," Carlos Ivan Marquez, head of the disaster unit, said.