Rebecca Ferrell, a spokesman for Colorado Parks and Wildlife, said: "It's an amazing story. Everyone is baffled and impressed. He had no weapons, no knives or trekking poles with him. How did he do it?"
The body of the mountain lion was found at the scene and was described as a "juvenile" thought to have weighed about 35kg. It was being tested to see if it were rabid, and the victim was being treated for any possible infections.
Experts initially questioned how the man could have got the better of the mountain lion, but an autopsy later confirmed suffocation as the cause of the animal's death.
Another spokesman for Colorado Parks and Wildlife said: "After additional investigation, including examination of the lion, we have confirmed the victim's account that he was able to suffocate the animal while defending himself from the attack."
Mark Leslie, a parks manager in Colorado, said: "The runner did everything he could to save his life. In the event of a lion attack you need to do anything in your power to fight back, just as this gentleman did."
Attacks are uncommon in Colorado - there have been three deaths and 16 injuries in the state in the last 30 years.
In 2016 a mother successfully rescued her 5-year-old son after he was attacked by a mountain lion near Aspen, Colorado.Across the US, fewer than 20 people have been killed by mountain lions in the past 100 years.