Six Italian scientists and a former government official are due to go on trial for manslaughter over the 2009 earthquake in L'Aquila.
The defendants are accused of giving a falsely reassuring statement before the 6.3 magnitude quake which devastated the Italian city and killed 309 people.
The defence argues that there is no way to predict major earthquakes even in a seismically active area, reported the BBC.
The scientists were part of a government panel tasked with assessing the risks after hundreds of low-level tremors had rattled the city in the months leading up to the lethal earthquake.
The panel issued a statement reassuring the city, although they added that it was not possible to predict whether a stronger quake would occur.