Israeli aircraft, tanks and gunboats pounded symbols of Hamas control in Gaza City in the heaviest night of bombardment in three weeks of fighting.
The strikes hit the home of the top Hamas leader in Gaza, Ismail Haniyeh, as well as government offices and the headquarters of the Hamas satellite TV station. Haniyeh was not hurt.
The escalation occurred as Benjamin Netanyahu bluntly rebuffed international pressure for a ceasefire and instead promised to extend Israel's three-week offensive against Gaza's Hamas rulers into a lengthy campaign that would bring more difficult days.
The Israeli Prime Minister said the military campaign in Gaza would not end until a network of tunnels Israel says have been dug to launch attacks against its citizens had been destroyed.
His unyielding stance came after yet another attempted truce collapsed amid renewed bloodshed that saw the deaths of at least eight Palestinian children and 10 Israeli soldiers.