Di Natale pointed to Australians who couldn't pay their medical bills, the homeless population, young people priced out of education and women who fear going home "because one woman a week is killed at the hands of a violent partner".
"And what have we got? We've got this spectacle. This disgrace. You should be ashamed of yourselves," he said.
Di Natale also took aim at the Government's policy paralysis, saying the Liberal Party walked away from climate change and energy policy, and ditched its economic plan to appease "dinosaurs inside your party room who held the Prime Minister to ransom".
"You are so focused on yourselves that you have forgotten what the country has elected you to do, and that is to govern for them, not for you," he said.
"You don't deserve to govern. You deserve to be turfed out. That's what you deserve."
Di Natale has earned praise for articulating the thoughts of frustrated Australians. A complete video of the speech has been viewed on Facebook more than 10,000 times and shorter clips are also being shared widely online.