The 18-month-old girl, known as Viola, was conceived with the help of artificial insemination after the couple's repeated applications to adopt a child were turned down on the basis that they were too old.
The four-judge panel ruled that "they [the parents] never thought about the fact that their daughter would be orphaned at a very young age, and before that would be forced to care for her elderly parents," a report in La Repubblica newspaper said.
The child is "the fruit of a distorted application of the enormous possibilities offered by genetic progress", the judges added.
They ruled that librarian Gabriella De Ambrosis, 57, and her retired husband Luigi, 70, were driven by "a narcissistic need to have a child" and showed "indifference with regard to the child's perspective".
- AAP