The issue of deportation, and particularly separation of families, has been a major question among communities of undocumented immigrants, with recent deportations ramping up those fears.
"I will do everything I can to prevent other families from facing what you are facing," Clinton, a former Secretary of State, told the woman. "And I will absolutely protect your children, yourself and try to bring your family back together."
Clinton also blasted Sanders for voting against a 2007 bipartisan immigration reform package. Sanders has said he voted against the bill because of a provision for guest workers, a programme he again called "akin to slavery".
Sanders also used the immigration issue to blast Trump, who has called for deporting the estimated 11 million undocumented immigrants in the country.
"Look, in this country immigration reform is a very hot debate. I would hope very much that as we have that debate we do not, as Donald Trump and others have done, resort to racism and xenophobia and bigotry," Sanders said.
"His idea of suddenly one day or maybe a night rounding up 11 million people and taking them outside of this country is a vulgar, absurd idea that I would hope very few people in America support."
Who came out on top
Winner
Hillary Clinton: This debate was a minefield for her. She was coming off of a disappointing loss in Michigan that gave Sanders some momentum. Clinton avoided a disaster and came out as the better debater, yet again. And despite a couple missteps - she still doesn't have a good answer on her Wall Street speeches?!? - she had some very strong moments that will likely endure more than anything else. When asked about her poor honesty ratings and her not-so-great public image, she had this to say: "I am not a natural politician, in case you haven't noticed, like my husband or President Obama." She added: "This is not easy for me."
Loser
Sanders: This was his chance, after a big win in Michigan, to change the course of the race. And he was aggressive. He tried. He's getting better. He even handled a very tough question (in South Florida, no less) about his past praise for Fidel Castro. But he didn't do anything to change the fact that Clinton remains the overwhelming favourite to win the Democratic nomination. Sanders will likely continue to amass delegates and win some states, but he still needs that game-changer to really make this a race. He didn't get it yesterday. And one wonders where else it might come from.
- AAP, Washington Post, Bloomberg