It underlined the acute strain Italy is under after its Government closed all but essential shops, businesses and industry in a desperate fight against the contagion.
There were fears the virus could spread from the worst-hit north to the more underdeveloped and dysfunctional south of the country.
At the weekend, Giuseppe Conte, the Prime Minister, announced a £356 million food voucher scheme to help struggling families.
"Nobody will be left alone. We need to help those who are struggling the most," he said, pledging that "the Government won't look the other way".
Regional politicians said help was needed urgently.
Leoluca Orlando, the Mayor of Palermo, warned: "If help from the Government arrives in two weeks - and another two weeks is needed to distribute it - then we run a big risk. The distress will turn into violence."
Social unrest was "exploding" across the south and could spread to the north, he said, calling the owners of bed and breakfasts, travel agents and gym instructors "the new poor".
In the south, there were fears that the economic downturn would be exploited by Mafia groups like the Camorra in Naples, Cosa Nostra in Sicily and the 'Ndrangheta in Calabria.
With failing businesses desperate for credit, Mafia organisations are likely to offer loans at exorbitant rates, or buy legitimate businesses with the proceeds of the drugs trade.
Nino Di Matteo, a former prosecutor in Palermo, said: "The bosses and their accomplices may have already started contacting businesses hit by the economic crisis. Organised crime could, in a short space of time, take control of numerous legal enterprises. We must not allow that."
Economists believe Italy's economic output could shrink by up to 7 per cent this year as a result of the lockdown.
Conte warned that unless there was massive aid to help the economic recovery of countries badly hit by the pandemic, nationalism and Euroscepticism would resurge.
"The number of unemployed we'll have after this tsunami will be very high. We must achieve reconstruction before that happens."
Italy was disappointed last week when EU leaders failed to come up with a plan to address the crisis.
Northern European countries, including Germany, rejected an appeal by nine EU member states, including Italy and Spain, to allow borrowing through so-called "corona bonds" to help cushion the economic blow of the pandemic.
Italy's lockdown, supposed to end on April 3, will almost certainly be extended, ministers said.