Senior aides of British Prime Minister Theresa May privately believe she is "finished" and may be forced to set out a timetable for her departure if she is to win the meaningful vote on her Brexit deal.
Two senior Downing Street figures are believed to have said that May should "fall on her sword" and announce she will quit so she is able to "go with dignity".
They believe she has permanently "lost the trust of Eurosceptics" and will have to make way for a new leader after the Conservative Party conference in October.
The Prime Minister is this weekend trying to win over Eurosceptics and Democratic Unionist Party (DUP) MPs ahead of a third vote on her Brexit deal on Wednesday.
Four Cabinet ministers including Philip Hammond, the Chancellor, yesterday held several hours of talks with the DUP in an attempt to win them over and give reassurances over the Irish backstop.