In the excerpts, Assad offered no evidence to back his charge that the U.S. was now backing the international terror group responsible for the September 11, 2001, attacks in the United States.
Extremist groups such as the al-Qaeda-affiliated Jabhat al-Nusra are gaining ground in Syria's two-year civil war. Jabhat al-Nusra, or the Nusra Front, has emerged as the most effective force among the mosaic of rebel units fighting to topple Assad.
Last week, Nusra Front leader Abu Mohammad al-Gonali pledged allegiance to al-Qaeda's leader, Ayman al-Zawahiri.
Washington has designated Jabhat al-Nusra a terrorist organization over its links with al-Qaeda. The Obama administration opposes directly arming Syrian opposition fighters, in part out of fear that the weapons could fall into the hands of Islamic extremists such as the Nusra Front.
Earlier this year, the U.S. announced a $60 million non-lethal assistance package for Syria that includes meals and medical supplies for the armed opposition.
On Wednesday (local time), Russian Foreign Minister Sergey Lavrov criticized an upcoming meeting of the Friends of Syria group in Istanbul - which brings together Western and Arab supporters of the Syrian opposition - and said efforts to isolate Assad and to arm the opposition were strengthening Islamic militants.
"If the priority is peace, changes and democratic reforms, it's necessary to force the warring parties to sit down for talks. If Assad's departure is the priority, the cost of such geopolitical approach will be more casualties," Lavrov said.
"If we allow those making the emphasis on (a) military solution to control the situation, those horrors ... will multiply and the terrorists' influence in the region will grow," he added.
The Syrian conflict began with largely peaceful protests demanding reforms and eventually turned into an insurgency and war in response to a brutal military crackdown on the protesters. More than 70,000 people have been killed, according to the United Nations.
In the TV interview, Assad also lashed out at Jordan, accusing his southern neighbour of allowing "thousands" of fighters to enter Syria across its borders.
His comments follow statements from U.S. and other Western and Arab officials that Jordan has been facilitating arms shipments and hosting training camps for Syrian rebels since last October.
"It's hard to believe that thousands are entering Syria with their equipment (from Jordan) when Jordan is capable of stopping or arresting a single person carrying light arms for the resistance in Palestine," Assad said.
Over the years, Syria has called Jordan a "puppet" of America because of its strong alliance with the United States. It's also accused Jordan of being a "spy" for Israel, with which Jordan maintains cordial ties under a peace treaty signed in 1994.
Assad's military is currently fighting to reverse rebel advances that have left vast stretches of northern Syria in the hands of opposition fighters. The government is also eager to shore up supply lines to its forces stretched thin by the fighting.
The Britain-based Syrian Observatory for Human Rights said the rockets struck the central Syrian village of Eastern Buwaydah and that two children and three women were among the 12 killed. Observatory director Rami Abdul-Rahman said rebels and government forces also engaged in heavy fighting nearby.
Eastern Buwaydah is located between Homs, Syria's third-largest city, and the Lebanese border. The region is of strategic value to Assad's regime because it links Damascus with the coastal enclave that is the heartland of Syria's Alawites and also home to the country's two main seaports, Latakia and Tartus.
Syria's regime is dominated by the president's minority Alawite sect - an offshoot of Shiite Islam - while the rebels are mostly from the country's Sunni majority. Assad's major allies, the Lebanese militant Hezbollah group and Iran, are both Shiite.
An amateur video posted online showed at least seven bodies, including a young girl with a bloody gash to her head, laid out on the floor of a room. A man can be seen wrapping the body of a boy in a white sheet as another man standing over them cries out, "Oh God, turn us victorious against Bashar. They killed innocent children."
"Is this child carrying a gun? This child is 12 years old," says the man, who appears to be the father of the dead boy. "Oh God. You gave him to me and now you are taking him."
The video appeared genuine and corresponded to other Associated Press reporting of the events depicted.
In the northwestern province of Idlib, rebels were attacking government troops Wednesday as anti-Assad fighters tried to check recent regime advances around the military bases of Hamadiya and Wadi Deif near the city of Maaret al-Numan.
Government forces killed more than 20 fighters in an ambush in the area on Saturday, allowing them to break the rebel hold on the countryside around the bases and ferry supplies to forces in the camps. For weeks, the military had to drop supplies in by helicopter to the besieged troops.
"The rebels are trying to re-impose a siege on the camps," Abdul-Rahman said. "They want to close the highway ... to stop them from supporting Wadi Deif and Hamadiya."
The fight for the two bases fits into the broader struggle for control of northern Syria. Most of the northern countryside is in the hands of anti-Assad fighters, while the regime is holding out in isolated military bases and most urban centers.
Maaret al-Numan lies along the main north-south highway linking Damascus to the northern city of Aleppo, where rebels and government forces have been fighting for control since an opposition offensive on the city last summer.
If the regime were to regain control of the highway, it would open up a badly needed supply route to its forces in Aleppo - potentially paving the way for further government advances in much of the rebel-held north.
- AP