Later, a visibly upset Lyshe appears to be sitting in a car and sending messages to friends.
"Pretty much everything we got is all up in flames. It's crazy," he said, as he lets out a deep sigh. "Now everything is gone."
Hours later, Lyshe took pictures and videos of what was left of his building, including the third-floor unit where he lived with his family. The roof of his unit had collapsed. Its hallways and rooms were covered with ashen debris.
"My room is completely destroyed, all my clothes. My closet was right here," Lyshe can be heard saying as he briefly aims his phone at a pile of rubble.
Down the hallway was his brother's room, he said, where pieces of burned wood were piled on the bed. His brother's closet appears to have been spared, with several pieces of clothing still intact.
"I'm kind of dealing with it right now. I'll start from scratch," he told the Cincinnati Enquirer. "It's like a dream ... everything is burned. I'll start fresh. It's all we can do now."
Authorities did not release the names of the residents, including the woman who started the fire.
Fire officials told reporters that this was the second fire in two weeks caused by someone trying to kill bed bugs.
A 2015 survey by the National Pest Management Association and the University of Kentucky found that bed bug infestations continue at high rates in the United States, with nearly all of the respondents saying they'd been treated for bed bugs in the past year. Infestations happened most often in nursing homes, office buildings, schools and day-care centres, according to the survey.
Do-it-yourself defences against bed bugs have resulted in accidental fires in the past.
In 2013, a 13-year-old boy trying to kill a bed bug doused the insect with alcohol and then lit a match, causing a fire to start in his apartment building.
In 2012, a Carlisle, Kentucky, woman set her apartment building on fire after she doused a couch in alcohol and accidentally dropped a lit cigarette on it. About 30 people lost their homes, while four were treated for smoke inhalation.
In Indianapolis that year, flames spread to a home after two men set their infested couches and two chairs on fire in the back yard.
Freel said homeowners and renters wanting to get rid of bed bugs should call pest professionals instead of trying to solve the problem themselves.