The carbon-fibre aircraft has been hailed for its low pollution and noise levels and its ability to hover above a variety of surfaces, including ice, deserts and water.
It can fly for five days without refuelling and cruise unmanned for two weeks at a time with a 10-tonne cargo.
Despite these impressive credentials, it has attracted ridicule on social media due to its slight resemblance to rather large buttocks.
A test flight was carried out in 2012, but its upcoming flight will be the first under the aircraft's latest specifications.
The date of the flight is yet to be announced, but it will be restricted to a 112km radius.
In a blog post, Hybrid Air Vehicles said a fuel module had been added to the aircraft this month, as well as the cockpit and payload bay.
"It's very satisfying for the team and me to get another milestone under our belts. We're hugely excited about the forthcoming Airlander first flight," said Mike Durham, Hybrid Air Vehicles' technical director.
Although the Airlander 10 is the largest aircraft in the world, bigger than the Airbus A380, it is still dwarfed by the zeppelins developed in Germany in the 1930s.