Drones came just 9m from colliding with an aircraft operating out of Teterboro Airport New Jersey.
The pilot flying out of a private airstrip in New Jersey avoided the remote-controlled aircraft, but airports including Newark Liberty International Airport, were closed by air traffic officials.
The airport carries 20 million passengers each year and serves nearby New York City, making it the 11th busiest airfield in the US.
This is thought to be the first incident of its kind in the State, following similar incidents at two London airports over Christmas.
In the UK, flights out of Gatwick and Heathrow were cancelled following drone sightings. Hundreds of flights were cancelled over the course of three days, leading to many days worth of delays over the busy Christmas period.