"It's all about who's true and who's not. I see a man who, although he's Brazilian, does not represent Brazil as he should.
"I feel he is very, very sloppy. I feel his shot selection is very poor. He has this tenseness in his body when he loads.
"We will enter and he will enter and try to close the distance but he will taste some strikes very early. It's like a slower, sloppier, more stuffed version of Aldo.
"I will guide him on to some strikes and as he's been KO'd before, I'll KO him again.
"It will be another KO, I'd love to beat the ugly out of him and drag it into the second or third round but I feel like I'm going to dust him in under one minute."
McGregor opted to move up a division rather than defend his 145lb title although he could do exactly that at UFC 200 in July.
And he added: "I chose this one because I came into this promotion as a two-weight world champion.
"I wanted to replicate that; that was the goal, to make history. This man across from me has a title but he has nothing else but that.
"He's a free-TV fighter. He has nothing to offer me other than that belt."
McGregor also claimed his opponent is not a 'true Brazilian' after leaving his homeland for California four years ago.
"I'll send him back to California, his home.
"I swear to God, at UFC 194 I fought Jose Aldo, I KO'd the country of Brazil's true champion.
"He never learned the language of his oppressor, he never came to America, he trusted his people, unlike this guy across from me.
"That's why the Brazilian people love Jose Aldo. When he steps off a plane, his people great him regardless of the result.
"We're sending Rafael on a four-day media run throughout Brazil and we've got to book him a hotel. I have got to book him a hotel in his own country.
"He will never receive a hero's welcome because he ran form Brazil. This guy, in Brazilian lingo, is a gringo."
Dos Anjos, who was subdued in the face of McGregor's verbal onslaught, replied: "The whole world has American dreams. This country has people from all different parts of the word.
"We have Irish, Brazilian and these people don't deserve to be called traitors.
"This guy is calling me a traitor just because I live here but I have my kids here, i have my family.
"I'm not a trash talker, I respect my opponents and I talk the truth.
"On March 5 I will send this guy home sad and I am going to keep my belt.
I'm a complete fighter. I fight standing, I fight on the ground.
"I beat Ben Henderson, Nate Diaz, Anthony Pettis, Donald Cerrone twice. I fought better guys, taller guys and stronger guys."