Samuels understands the importance of the race, which is why she put health problems behind her to compete alongside Debbie Tanner in the women's field.
"Originally, I was looking for a good result in San Diego to keep my points up to make sure we get that third spot for the Olympics," Samuels said. "But the night after the Olympic announcement in Auckland, my plans changed.
"I had a problem with my stomach again and, two days later when I was back in Wanaka, I visited the doctor and ended up in the emergency department in Dunedin that night. The next morning I was in surgery getting my abscessed appendix out."
Less than three weeks later she is lining up in San Diego. Samuels wasn't expecting miracles during the race, given the amount of training she had to miss, but she was aiming to get her fitness up before the next world championship race in Madrid.
"I am not sure how this race will go with so much time in hospital and recovering at home, but I can only give it what my best. Following this race I head straight to Europe where I will stay in Sete (southern France) until the Madrid world series race."
In the men's field, Olympians Bevan Docherty, Kris Gemmell and Ryan Sissons are joined by Clark Ellice and Tony Dodds on the start line for New Zealand.
"I'm looking forward to San Diego this weekend," said Sissons, in the same position of Samuels.
"Another good result for the team will go some way towards confirming the three spots for New Zealand at London - this is our big goal."