Serena Williams suggested she won't go to Japan if coronavirus protocols mean she can't bring her 3-year-old daughter with her.
"I haven't spent 24 hours without her, so that kind of answers the question itself," Williams said. "There is this pandemic and there is so much to think about."
And on Sunday, second-ranked Naomi Osaka sounded conflicted about the games' status.
"Of course I would say I want the Olympics to happen, because I'm an athlete and that's sort of what I've been waiting for my entire life," Osaka said. "A lot of unexpected things have happened and if it's putting people at risk, and if it's making people very uncomfortable, then it definitely should be a discussion, which I think it is as of right now."
Japan has attributed 11,000 deaths to COVID-19, better than many countries, but poor for Asia. The virus and its spreading variants are taxing Japan's health-care system with only 2% of the population vaccinated.
Public sentiment in Japan continues to run against holding the Olympics in the middle of a pandemic. Between 60-80% of Japanese people in polls have said the Olympics should be canceled or postponed.
But local organizers and the International Olympic Committee insist the games, which were already postponed by a year, will open as planned on July 23.
"I know you still have two, three more months. It's tough to really say right now," Nishikori said, adding that he thought organizers should "hold" on making a decision for now.
The 45th-ranked Nishikori, a former U.S. Open finalist and Japan's top male player, said that if the Olympics were opening now, he thinks it would be "really tough" to hold the competition.
"If you think only about athletes, I think you can do it," he said. "If you can make a good bubble, maybe you can do it, but there is some risk, too."
"(What happens) if there is 100 cases in the village ... (or) thousands?" Nishikori asked. "You have to really discuss how you can play really safely."