"Bro I didn't even move to break him. He hit a double, missed the ball long, missed the ball long. I just stood there and slapped one winner, he literally just broke himself.
"Did not move, I can just stand there and serve and not really move. It's annoying β¦ it really hurts."
Kyrgios then threw his towel over the camera, forcing the broadcasters to switch to an overhead view.
The injury continued to plague Kyrgios throughout the second set as the two men went back and forth.
But it was during the ninth game of the set where Kyrgios was tipped over the edge, this time his outburst was due to the service clock and it was chair umpire Fergus Murphy who copped the full brunt of his outbursts.
On several occasions the clock was left with only seconds remainin, forcing Kyrgios to race through his first serve.
He had words for Murphy and continued all the way to his seat, bringing up notorious slow server Rafael Nadal.
"You're telling me Rafa plays that quick every service ball? That's hilarious bro, hilarious," Kyrgios said to Murphy.
"I missed the ball, the guy starts the clock.
"If Rafa plays that quick I'm retiring. Retiring from tennis.
"Absolute rubbish β¦ disgrace.
"Get me some footage of Rafa playing that quick, that game. If you can find any of that I'll shut my mouth and never speak again.
"I guarantee you'll find none of that, none of it."
The outbursts from Kyrgios continued as the match got back underway with the broadcasters forced to apologise for the obscenities as he continued to drop F-bomb after F-bomb.
Khachanov secured the second set to force the match into a deciding third set, but as the two men got back to their seats it was Kyrgios who unleashed over Murphy's umpiring.
"The worst f***ing ref ever, the worst ref in the game," Kyrgios shouted at the top of his lungs.
"The worst, hands down. Every time I play he's doing some stupid sh*t, every time."
The outburst earned Kyrgios a court violation from Murphy who had clearly had enough of being targeted with the profanity.
After asking to head to the bathroom, Kyrgios walked off the court holding two racquets. The cameras in the hallway captured him slamming the two into the walls before he walked back out onto the court.
Murphy radioed through to the backroom to check why he had returned with two destroyed racquets but the Aussie escaped a warning after it wasn't picked up by any of the other umpires.
As Kyrgios' mind remained focused on the service clock and going after the chair umpire, Khachanov took advantage in the deciding set and claimed the victory.
But after the two men met at the net, Kyrgios wasn't finished with Murphy and as he made his way towards the umpire he unleashed once again.
"You're a f***ing tool bro," Kyrgious said before appearing to spit in the direction of the umpire.
The ugly scenes from the fiery Australian drew the ire of the commentators who proclaimed the showing was "disgusting".
"We haven't heard the end of this and from what he did at the end was quite frankly, truly disgusting and a big fine for Kyrgios," one commetator said.
Khachanov now moves into the third round and will take on Frenchman Lucas Puille after he comfortably took care of Canadian Denis Shapovalov 6-4, 6-4.
"He has a really great talent but sometimes the head not in the right place," Khachanov said.
"It was a really difficult match for me β I had to really work it out, how to get the win.
"It's really tough (playing Kyrgios), not only for me but for everybody. You have to try and handle it, then you can have chances to win the match. Always try to stay in there."