"It's nice to play against different game styles ... he's quite different in coming to the net a lot and trying to get forward at every opportunity," Murray said. "When he serves well, it's easy to get impatient because you don't touch the ball, sometimes for a whole game.
"He didn't start off the match serving so well, which helped me. But when he picked his serve up in the second set, it became much tougher."
Murray will face 32nd seed Joao Sousa or Colombian Santiago Giraldo in the third round as he strives to go one better in 2016 after losing four finals at Melbourne Park.
Two-time champion Victoria Azarenka continued her near-faultless run yesterday, crushing Danka Kovinic 6-1, 6-2 in the second round.
Azarenka is seeded 14th but on form is shaping as Serena Williams' biggest challenger at Melbourne Park.
The 26-year-old, who won the Open in 2012 and 2013, dished out a double bagel in the opening round.
Having ended Alison Van Uytvanck's campaign in just 53 minutes, Azarenka accounted for Kovinic in just a tick over an hour. She has dropped three games in the tournament so far.
"I really don't count the games," Azarenka said courtside. "I just enjoy myself on the court and try to play every point like it's my last point."
Azarenka is back to full fitness after a frustrating 2015 campaign, during which she failed to progress beyond the quarter-finals at any grand slam.
The Belarusian won the Brisbane International earlier this month and has continued her strong form since.
She noted it was hard to compare her current tilt at Open glory with the success she enjoyed in 2012 and 2013.
"Where I am in my life is very different and I'm so very happy to be here and want to enjoy it as long as I can," Azarenka said.
"I know it's a long way to go [to the final] so I like to approach it day by day. Stay in the moment and enjoy."
Azarenka next faces Naomi Osaka, an 18-year-old on grand slam debut, who ousted 18th seed Elina Svitolina 6-4, 6-4.
Third seed Garbine Muguruza recorded a 6-4, 6-2 victory over Kirsten Flipkens in her second-round clash. Muguruza is yet to drop a set in the tournament and next faces world No48 Barbora Strycova.
Top results
• 2-Andy Murray (GBR) bt Samuel Groth (AUS) 6-0 6-4 6-1
• 10-John Isner (USA) bt Marcel Granollers (ESP) 6-3 7-6(6) 7-6(2)
• 3-Garbine Muguruza (ESP) bt Kirsten Flipkens (BEL) 6-4 6-2
• 20-Ana Ivanovic (SRB) bt Q-Anastasija Sevastova (LAT) 6-3 6-3
- AAP