Murray withdrew from the Swiss Indoors, claiming a back niggle, to the dismay of organisers faced with his second pullout in as many years.
Federer is trying to avoid pressure as the race to the year-end No 1 ranking goes down to the wire with Djokovic pushing hard and results in Paris a key to any possible movement in the table.
"I have to think day by day. It's simple, it's pretty routine, but it's my only way to handle these next couple of crazy weeks," said the Swiss.
"I want to play well at the World Tour Finals, there's no question about that. It's the highlight of the end of the season and one of the biggest events we have in the sport."
Spain's David Ferrer takes the fourth seeding ahead of Czech Tomas Berdych, and a trio of players attempting to clinch berths for London next - France's Jo-Wilfried Tsonga, del Potro and Serb Janko Tipsarevic. Spaniard Nicolas Almagro and France's Richard Gasquet hope to gain the last two spots.
- AAP