Djokovic surrendered a 4-2 fifth-set advantage to Nadal in the 2013 semifinals and was thwarted once again by the Spaniard in last year's championship decider.
This year, though, Nadal looks a shadow of the claycourt colossus who boasts nine French Open crowns and whose lifetime record at Roland Garros stands at a staggering 66 wins - including six over Djokovic - and just one defeat.
Nadal has been trumped five times on dirt and his lone title so far in 2015, as he battles back from nagging injuries, came in Buenos Aires without having to beat a single player inside the world's top 60.
Turning 28 today, Djokovic believes his time has come and is vowing to stick to the formula that has yielded 12 titles in the past 13 months.
"I don't think I need to gear up or do anything special in order to be successful at Roland Garros," he said.
"I have been very close to that title before, played several finals. I just need to continue preparing myself for that event as I prepare for any other, try to keep the routine going and hope it will take me where I want to be."
Seventh in the rankings after being unable to collect a European claycourt title en route to Paris for the first time in a decade is certainly not where Nadal wants to be.
Handed his lowest seeding since triumphing as a teenager on debut a decade ago, the 14-times Grand Slam champion looms more as an x-factor than a fearsome force.
The Majorcan's malaise has Federer seeded to make the final for a sixth time but avoiding Nadal's half of the draw will still be a relief to the defending champion's chief rivals.
Turning 34 in August, Federer would likely need to conjure a first victory over Djokovic at a slam in three years - and possibly also a first against Nadal since 2007 - to become the oldest champion in more than four decades.
But the Swiss great dismisses the notion the tournament shapes as a battle in two. "It's all talk. In the end, the racquets do the talking," Federer said.
Andy Murray, a two-time semi-finalist in Paris, had failed to win a title on clay in 10 years but suddenly picked up two in six days in Munich and Madrid to emerge as a challenger.
Triumph at Roland Garros would put Djokovic with legends Laver, Federer, Nadal and Andre Agassi as only the fifth man in 47 years of professional tennis to win all four majors - Wimbledon, the Australian, French and US championships - at least once each.
- AAP