The experience and consistency of No4 seed Svitolina proved far too much for the precocious talent of teen sensation Marta Kostyuk in an all-Ukrainian third-round encounter.
Svitolina - the only seeded player remaining in her quarter of the draw - won 6-2 6-2.
Her next opponent will be Czech qualifier Denisa Allertova, who moved into the last 16 at a major for the first time with a commanding 6-1 6-4 win over Poland's Magda Linette.
Pre-tournament title favourite Svitolina won Brisbane two weeks ago and is among five women in contention to replace Simona Halep as world No1, depending on results at Melbourne Park.
She needed only 59 minutes to end the campaign of 2017 Australian Open junior champion Kostyuk, who committed 31 unforced errors, compared with only 11 from the racquet of Svitolina. "It is very special for me," said the 23-year-old Svitolina, after reaching the last 16 at the Australian Open for the first time.
"It's sad that it was against a Ukrainian girl. That's always tough. [Kostyuk] always fights until the end.
"She has a very bright future and you're definitely going to hear a lot more about her."
Kostyuk sobbed into a towel in the tunnel soon after leaving the court, but could joke about the defeat when asked later what she could take out of the experience.
"Well, a lot," she said. "How much you have to pay Svitolina to have one-hour lesson? I got it for free."
Petra Martic overcame the aggressive approach of Thai qualifier Luksika Kumkhum to move into the fourth round. Kumkhum dominated the winners' count 44-16 but the the steadiness of Martic proved crucial as the unseeded Croatian advanced 6-3 3-6 7-5 in a match lasting two hours and 10 minutes.
It was a double celebration for Martic, who turned 27 yesterday but she too struggled with the heat. "Today was really just 'try your best and survive until the end'."
Last Brit standing Kyle Edmund continues to fly the Union Jack, advancing to the round of 16 after surviving a torrid five-set battle with Nikoloz Basilashvili, 7-6 (7-0) 3-6 4-6 6-0 7-5 after three hours and 34 minutes
●In the men's doubles, Kiwi Artem Sitak and Dutch partner Wesley Koolhof were knocked out 6-7 (5-7) 6-4 6-4 by seventh seeds Oliver Marach and Mate Pavic, the Austrian/Croatian combination, who won the ASB Classic doubles title in Auckland last week.
●Coco Vandeweghe has been fined $10,000 for unsporting conduct for screaming an obscenity at her first-round opponent, Timea Babos. Vandeweghe said she was irritated by what she described as excessive celebrating by her Hungarian opponent during their match in which Vandeweghe was assessed a code violation for the obscenity and delay of game for insisting on eating a banana during a changeover.
- AAP