Wallabies coach Michael Cheika has overhauled his team, making seven changes to the starting line-up to face Argentina with Michael Hooper and Quade Cooper among the casualties.
Despite last week's last-gasp win over South Africa to open Australia's Rugby Championship campaign, Cheika has put a broom through the side for Saturday's clash in Mendoza as he continues to search for his best line-up ahead of the two Bledisloe Cup clashes with New Zealand then the World Cup.
David Pocock has won this round's battle for the openside flanker role, relegating fellow former captain Hooper to the bench.
Cheika resisted the temptation to start his two world-class fetchers - Pocock and Hooper - together in his backrow and recalled Ben McCalman at No.8 in place of Scott Higginbotham, who drops out of the match squad.
In the other change to the starting pack, renowned scrummager Greg Holmes get his first Test start in eight years, replacing prop Sekope Kepu, who drops to the bench.