Blues prop Alex Hodgman and flanker Tom Robinson have been ruled out of the team to play the Hurricanes at Eden Park due to concussion.
Wing Caleb Clarke is out with illness, with Tanielu Tele'a straight back into the starting line-up for the match on Friday after his four-week suspension for a mid-air collision in the win over the Stormers. Tele'a, only 20 and in his first year at this level, has been one of the Blues' best before his suspension.
There are also several selection changes as coach Leon MacDonald looks to shake things up following his team's 26-21 defeat in Canberra, including Harry Plummer replacing Otere Black at first-five. Wing Rieko Ioane is back after an All Black-enforced break last week.
"We are clearly disappointed with our overall performances in the last three games away. There have been lots of good aspects in each of those games but there have been one or two aspects in each of them that have let us down," MacDonald said.
"We are looking to put a complete performance together, one that we can be proud of and one that our fans deserve.