Marino Mikaele-Tu'u is the latest to fall in the Highlanders' injury-plagued season.
The dynamic loose forward will miss the remainder of Super Rugby Aotearoa, having sustained a stress fracture in his leg.
He is one of two players missing due to injury for the side's final match of the season against the Hurricanes in Wellington tomorrow.
Highlanders coach Tony Brown said it was disappointing to lose Mikaele-Tu'u, a player firmly in the sights of All Blacks selectors last year, especially as he is the side's eighth player ruled out for the season.
"It's a bit consistent with the rest of our guys," he said.