They have a chance against a Reds side also spluttering through the 2012 season. The defending champions have won four and lost four to sit 10th, seven points outside the top six.
The Queenslanders were beaten 23-13 by a clinical Stormers outfit nearing the end of an arduous tour of New Zealand and Australia and will want to beat the Blues to boost their own playoffs aspirations.
The Blues will need to show plenty of character to overcome another blow this week, after prop Tony Woodcock was ruled out with a calf strain he picked up in training on Wednesday.
He joins fellow All Blacks Keven Mealamu (calf), Jerome Kaino (shoulder) Isaia Toeava (hip) and Anthony Boric (neck) on the sidelines and his place in the starting side will be taken by Tevita Mailau.
They will be boosted by the return of wing Rudi Wulf, who missed last week's 30-27 defeat to the Highlanders with a shoulder injury, and Piri Weepu will start after shedding more than 5kg since joining the Blues.
The halfback turned up to the Blues about 10kg above his optimum playing weight, and he has been playing Wellington club rugby for Wainuiomata on top of his commitments with the Blues in an effort to get match fit.
"He's made massive gains," Lam said before catching himself. "Losses, if you like. He's finally cracked the 100kgs. He's into the 90s now, which is great, and his skin folds have come down quite a bit. We saw the impact he made at the weekend. He has been working tirelessly behind the scenes and has done well enough to get a start.
"There's no doubt he's world-class, we know that, it was just about him getting to a position where he could do that consistently on the field. Another week, and he's done more work. I have seen the gains with the stats and the gains on the field."
Blues: Hadleigh Parkes, George Moala, Rene Ranger, Ma'a Nonu, Rudi Wulf, Gareth Anscombe, Piri Weepu, Peter Saili, Luke Braid (c), Daniel Braid, Filo Paulo, Ali Williams, Charlie Faumuina, Tom McCartney, Tevita Mailau. Reserves: James Parsons, Pauliasi Manu/Angus Ta'avao, Liaki Moli, Chris Lowrey, Alby Mathewson, Michael Hobbs, Benson Stanley.