While Gatland has named two quality England locks in Courtney Lawes and Maro Itoje for the Blues match, he is clearly going to name a near test-strength side for the Crusaders at AMI Stadium on Saturday and there is a danger that a fired-up challenge from Tana Umaga's men could catch his side out like the Provincial Barbarians so nearly did.
Umaga has named eight All Blacks in his starting line-up, including a star-studded backline with pace and explosiveness which has the potential to stretch the visitors in every way.
"They've got some real quality individuals that we have to take care of but we're excited about the game, we're looking forward to it," Gatland said.
"The Blues have only lost to one non-New Zealand side - it shows how strong they are.
"It's just reinforced how tough this tour is going to be. The Provincial Barbarians, they were pumped up, they were fired up in the changing rooms - it was a massive opportunity for them."
In looking ahead to what is going to be a torrid challenge from the Crusaders, unbeaten after 14 Super Rugby matches this season, it appears clear that Irishman Conor Murray will start at halfback, inside England No10 Owen Farrell.
Welsh outside backs Liam Williams and George North are almost certain starters at AMI Stadium, as is England prop Maka Vunipola.
In the meantime, Gatland's new boys, including one Jared Payne, a former Blues player and adopted Irishman, have the opportunity to put a new perspective on a tour which has begun so unconvincingly.
Northlander Payne, starting at centre after recovering from a calf injury which kept him out of the tour opener, said: "It's going to be bloody tough. They're a pretty good team so we're going to have to be on our toes. If we give those boys too much space they could cause us headaches."
Lions: Leigh Halfpenny, Jack Nowell, Jared Payne, Robbie Henshaw, Elliot Daly, Dan Biggar, Rhys Webb, CJ Stander, Justin Tipuric, James Haskell, Courtney Lawes, Maro Itoje, Dan Cole, Ken Owens (c), Jack McGrath
Reserves: Rory Best, Joe Marler, Kyle Sinckler, Iain Henderson, Peter O'Mahony, Greig Laidlaw, Johnny Sexton, Liam Williams
Blues: Michael Collins, Matt Duffie, Rieko Ioane, George Moala, Sonny Bill Williams/ TJ Faiane, Stephen Perofeta, Augustine Pulu, Steve Luatua, Blake Gibson, Akira Ioane, Scott Scrafton, Gerard Cowley-Tuioti, Charlie Faumuina, James Parsons, Ofa Tu'ungafasi.
Reserves: Hame Faiva, Alex Hodgman, Sione Mafileo, Patrick Tuipulotu, Kara Pryor, Sam Nock, Ihaia West, TJ Faiane/Melani Nanai