Hurricanes captain Dane Coles and wings Nehe Milner-Skudder and Cory Jane must pass fitness tests before being considered to play the Blues at Eden Park on Friday.
Coles, who has missed the opening two rounds of the season due to hamstring and calf strains, has been bracketed with young hooker Leni Apisai.
The right wing spot has been left open with Milner-Skudder recovering from a bruised knee suffered during the opening round loss to the Brumbies and Jane working through concussion protocols after taking a knock against the Highlanders in Dunedin.
Depending on who is available, the No 14 jersey and the final bench spot could go to Milner-Skudder, Jane, Jason Woodward or Pita Ahki.
Hurricanes coach Chris Boyd said the sensible option was to err on the side of caution with all three injuries.