Wallabies veteran Drew Mitchell and lock Kane Douglas have been dropped for Saturday night's Rugby Championship clash with Argentina in Perth, while prop Tom Robertson is a chance to make his international debut from the bench.
Douglas has been replaced in the starting side by Rob Simmons, who will partner Adam Coleman in the sixth different lock combination used by Michael Cheika in 2016.
Mitchell returned from injury off the bench in last week's win over South Africa, but he has been replaced in the squad by Henry Speight.
Mitchell is still building up his match fitness, and he's expected to be in line for a starting berth for upcoming matches away to South Africa and Argentina.
Speight hasn't featured in the Test arena since facing Uruguay at last year's World Cup.