The Wallabies have been hit with another blow a day before their test against the Springboks, with star No 8 David Pocock being ruled out because of a concerning neck injury.
Pocock was unable to recover from ongoing neck soreness and stiffness he suffered during the Wallabies' second Bledisloe Cup loss against the All Blacks last month.
The exact nature or extent of Pocock's neck issues were not revealed, but he was not able to participate in contact drills in training this week.
Former Crusader Pete Samu - who isn't a noted no 8 - will replace the injured star in the Wallabies' starting lineup.
Head coach Michael Cheika hasn't commented on Pocock's injury, but after naming him in his initial team on Wednesday, he said the Wallabies team needed to protect Pocock a bit more at the breakdown.