They were again cruelled on the injury front, losing Jack Murchie and Eliesa Katoa to concussion in the first half, then lost Addin Fonua-Blake midway through the second half.
In the first half the Warriors endured probably their worst 20-minute spell of the season, conceding five tries. At times it looked like a training run for Wayne Bennett's team, as they broke the line at will.
The Warriors had been their own worst enemies, with several soft errors, something you can't afford against any team, let alone an established top-four outfit.
In the midst of the carnage on Saturday, the Warriors scored some nice tries, but it was scant consolation.
Few players emerged with any credit, though Dallin Watene-Zelezniak ran with gusto and Josh Curran got through 51 tackles
The Warriors made an ideal start, as Watene-Zelezniak snaffled a loose ball and sprinted from halfway. It was a nice moment for the new recruit, who had missed the birth of his child on Friday night, with his wife in New South Wales.
Unfortunately, the bright beginning didn't last. The Warriors seem to make more unforced errors than any other NRL team, and it continued with some early mistakes from Reece Walsh.
The first was unfortunate – as his kick hit the back of a Rabbitohs forward – but the next two were poor. The teenager put an attacking bomb a couple of metres over the sideline, then sent a kickoff beyond the dead ball line.
That meant instant pressure and the Rabbitohs didn't need a second invitation. They embarked on an attacking blitz, with five tries in 20 minutes. Tom Burgess powered over twice from close range, as it appeared that all the homework on the big English unit had been forgotten.
South Sydney had some brilliant touches, with Latrell Mitchell's pass to set up Cameron Murray one of the offloads of the year, as the fullback flung a pass from nowhere while being driven to the ground.
But mostly it was just poor defence, at times embarrassing, and far from first-grade standard. The Warriors were on their heels, not advancing to pressure the Souths playmakers. The defensive structure went missing and contact was half hearted, as they were continually exposed up the middle.
There was a late first-half recovery, with two tries in four minutes before the break.
Marcelo Montoya crossed acrobatically, after smart lead up work from Kodi Nikorima and Chad Townsend. Their third try was even better, with Nikorima backing up after setting Watene-Zelezniak free down the sideline with a beautiful pass.
But any hope of a revivial was extinguished within 90 seconds of the second half, as Jaydn Su'A powered through four defenders.
Josh Mansour – in his first NRL game for months – eased his way away to a second-half brace – before Walsh briefly stemmed the bleeding, anticipating Townsend's clever kick.
But the Rabbitohs engineered two more tries, to hit their biggest ever tally against the Auckland club.
Rabbitohs 60 (Tom Burgess 2, Jaydn Su'A 2, Josh Mansour 2, Jaxson Paulo, Cameron Murray, Cody Walker, Keaon Koloamatangi, Latrell Mitchell tries; Adam Reynolds 7 cons, Latrell Mitchell con)
Warriors 22 (Dallin Watene-Zelezniak, Marcelo Montoya, Kodi Nikorima, Reece Walsh tries; Walsh 3 cons)
Halftime 34-16