The reunion of the two giant wings comes more than 13 months after they were first used together, ironically when the Warriors were last in Perth facing the Rabbitohs in June last year.
Aside from Lolohea's shift, there are two changes to the starting pack used in the 27-18 win over Gold Coast.
Captain Ryan Hoffman is back after a virus prevented him playing in Simon Mannering's 250th NRL game while Albert Vete (hamstring injury) has been ruled out.
His absence sees Ben Matulino and Jacob Lillyman named as the starting props, Lillyman set to back up after lining up for Queensland in the final State of Origin clash against New South Wales in Sydney tomorrow night.
Charlie Gubb, who started at loose forward against the Titans, switches back to a five-man bench alongside Lolohea, Sam Lisone, Bunty Afoa and James Gavet.
After distinguishing himself on debut against Gold Coast, Afoa backed up with 80 minutes for the club's Intrust Super Premiership side last weekend, making 92 metres from nine runs as well as 43 tackles in a 12-8 win over Illawarra.
Gavet, in line for his seventh NRL outing of the year, has been impressive for the reserve grade side over the past month with 160 metres and 34 tackles against North Sydney, 174 metres and 35 tackles against Wests Tigers and 147 metres and 30 tackles against Illawarra last Saturday.
The Warriors take an 8-8 win-loss record into Saturday's contest. With eight rounds to go in the regular season they're seventh on the table on 20 points while the Sea Eagles are 13th on 14 points.