Gray then scored himself from a John Sutton kick two minutes later as the home side wrested control of the match, against a tough but unlucky Manly.
Gray has scored seven tries in his first eight NRL games and his emergence comes on the back of fellow Bunnies winger Alex Johnston's sensational rise last season.
Souths' win is soured somewhat by a concussion to Adam Reynolds who was taken off in the 24th minute.
Tom Symonds (cheekbone) is an injury concern for Manly.
Souths back-rower Glenn Stewart was solid in his return from a thumb injury against his former club, while Rabbitohs props George and Tom Burgess put in two of their better efforts of the year, playing against brother Luke for the first time.
Kieran Foran was one of Manly's best after spending the week in the headlines due to his contract standoff with Parramatta.
Two first half hits from Jorge Taufua on Dylan Walker and Steve Matai on Dave Tyrrell were contenders for tackle of the year.
Matai gave Manly some hope when he crossed in the 55th from a clever short side play engineered by Foran.
But Luke Keary hit back for the Rabbitohs in the 64th minute from a hot potato pass from Johnston after he chased down the five-eighth's kick.
Coach Michael Maguire was happy with the effort from Souths, after they recorded their heaviest loss under him in their last outing.
"It was a big turnaround in a couple of weeks ago," he said.
"It was a tough effort out there, especially in defence when we held them back for 20 or 25 tackles in the first half."
Manly mentor Geoff Toovey was unhappy Goodwin's try was overturned by the video referee.
"I can't talk about it and I can't explain it," he said.
Toovey said Manly's error rate cruelled them.
"We let them back in with a some silly mistakes," Toovey said.
"I thought we dominated them in the first half but they came out with more enthusiasm after half time and came away with the win."
- AAP
