He said the recovery techniques and solid pre-season would give the 28-year-old every chance to not only stay on the field, but recapture the form that led him to sharing the Dally M Medal with Johnathan Thurston in 2014.
Hayne has slimmed his figure to better cope with the extra workload required of the modern-day fullback.
"We know how Jarryd can play, the question will be getting back to that standard, or the challenge for him is being even better than he was before on a consistent basis," Henry told The Saturday Telegraph.
"Plenty of players have improved at the back end of their careers. 'JT' (Johnathan Thurston) has been sensational, Cooper Cronk, Cameron Smith, these guys are past 30 but at the top of their games.
"Darren Lockyer went out on top of his game. Some guys can mature, get wiser and play smarter. Hopefully Jarryd is one of them and has his best footy ahead of him.
"He has high standards. He has aspirations to play on the big stage, wants to play Origin and is hungry to play in that environment."
Henry said Hayne's lack of match fitness was the only reason he spent time in the halves last season.
"He'll be fullback, there's no need for him to be in the halves," said Henry, who has Ash Taylor, Kane Elgey and Tyrone Roberts fighting for a spot in the halves.
Henry said player burnout could not be ignored but he said as long as Hayne emerged unscathed from the Nines, he would play around 40 minutes against the Indigenous All Stars on February 10.
The following weekend Hayne will play the Titans' final pre-season game against the Warriors.
Henry could understand the Rugby League Players Association pushing for longer holidays but also felt the need for a balance with representative commitments.
"The primary role for the players is to play footy for their clubs who pay their wages," Henry said.
New South Wales coach Laurie Daley indicated last week that he would take on Hayne as well as fellow fullbacks Matt Moylan and James Tedesco if they started the season well.
If Hayne is left out of the Australian side for the World Cup, eligibility rules allow him to immediately switch his allegiance to Fiji, who he previously starred for in the 2008 World Cup.
The Hayne Plane is a frequent flyer
2015: EIGHT NFL games
2016: FIVE rugby sevens games for Fiji
SIX NRL games for Gold Coast Titans
2017: Auckland Nines
World All Stars
Trial in New Zealand
24 NRL games
3 Origin games
World Cup for Australia or Fiji