"He's one of those blokes that's built for Origin," Hindmarsh said.
"16 Origins at just 25 ... that's a lot of experience already.
"What can you say about him? He knows how to play the game.
"He's big, he's powerful and we all know what he can do when he does get in that Blues jersey.
"The level that he plays goes up a notch and I'm sure he'll be there doing his best to win it for the Blues.
"I'll guarantee he'll make more than one break on [Wednesday] night."
Hayne claimed the 2009 Dally M medal on the back of his outstanding offensive play - scoring tries, making breaks and driving the Eels to an unlikely grand final berth.
But in recent weeks Hayne has produced several terrific defensive plays, making miracle try-saving tackles against Brisbane and North Queensland while crunching St George Illawarra's Josh Dugan in monster hits.
"And making those tackles is what Origin is all about," Hindmarsh adds.
"Sometimes those try-savers can win you the games.
"As much as you need to score points you've got to stop them as well.
"Hopefully we don't need to see him use any of those try-savers, but it's good to have someone that's big and strong at fullback."
- AAP